A Universal Model for Spike-Frequency Adaptation
نویسندگان
چکیده
منابع مشابه
A Universal Model for Spike-Frequency Adaptation
Spike-frequency adaptation is a prominent feature of neural dynamics. Among other mechanisms, various ionic currents modulating spike generation cause this type of neural adaptation. Prominent examples are voltage-gated potassium currents (M-type currents), the interplay of calcium currents and intracellular calcium dynamics with calcium-gated potassium channels (AHP-type currents), and the slo...
متن کاملSpike-Frequency Adaptation
When stimulated with a constant stimulus, many neurons initially respond with a high spike frequency that then decays down to a lower steady-state frequency (Fig. 1 A). This dynamics of the spike frequency response is referred to as “spike-frequency adaptation”. Spike-frequency adaptation is a process that is slower than the dynamics of action potential generation. Spikefrequency adaptation by ...
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Spike-frequency adaptation is a common feature of neural dynamics. Here we present a low-dimensional phenomenological model whose parameters can be easily determined from experimental data. We test the model on intracellular recordings from auditory receptor neurons of locusts and demonstrate that the temporal variation of discharge rate is predicted with high accuracy. We relate the model to b...
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The brain can reproduce memories from partial data; this ability is critical for memory recall. The process of memory recall has been studied using autoassociative networks such as the Hopfield model. This kind of model reliably converges to stored patterns that contain the memory. However, it is unclear how the behavior is controlled by the brain so that after convergence to one configuration,...
متن کاملSpike frequency adaptation and neocortical rhythms.
Spike-frequency adaptation in neocortical pyramidal neurons was examined using the whole cell patch-clamp technique and a phenomenological model of neuronal activity. Noisy current was injected to reproduce the irregular firing typically observed under in vivo conditions. The response was quantified by computing the poststimulus histogram (PSTH). To simulate the spiking activity of a pyramidal ...
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ژورنال
عنوان ژورنال: Neural Computation
سال: 2003
ISSN: 0899-7667,1530-888X
DOI: 10.1162/089976603322385063